Hyperpigmentation of the skin

What is Hyperpigmentation (skin darkening)?

It is a darkening of the skin that happens due to an increase in melanin production, and an increase in its deposition in the skin.

Symptoms may affect multiple parts of the body. Understanding which part of the body a symptom affects, can help us to better understand the potential underlying causes of a symptom, including a rare disease or genetic syndrome.

Skin is a part of the integumentary system of the body, a system which includes not only skin but also hair and nails too. The integumentary system acts to protect our body from external threats or injury.

Generally, symptoms affecting the skin can be seen with the eye. Although diagnosing a skin related symptom may involve different tests and assessments, both subjective and objective.

Symptoms relating to the skin may be temporary or permanent and covers conditions including rashes, hives, lesions and discolouration. They may affect the tone, texture and appearance of the skin in different ways. They may also cause some level of discomfort, including itching and or some level of pain.

What should I do next?

In some instances, hyperpigmentation of the skin may be one of the features of a rare disease or genetic syndrome. To find out if someone with Hyperpigmentation, may be due to a genetic syndrome, it is important to have a consultation and evaluation with a clinical genetic specialist. Specialists may also suggest specific genetic testing or other types of tests to help reach a diagnosis. FDNA’s AI technology can help speed up the diagnostic process by analyzing facial features and other health information.

More signs and symptoms

Signs & Symptoms

Hyperkinetic Movements

Hyperkinetic movements are repetitive, abnormal and involuntary movements of the body. These motions are identified as common neural disturbances in children and can potentially lead to movement disorders. The distribution and severity of these repeated movements may shift over time.

Read more
Signs & Symptoms

Rieger Anomaly

Reiger anomaly is an ocular defect characterized by serious deformity in the anterior chamber of the eye with noticeable strands and shrinking of the iris stroma. This congenital malformation of the anterior segment is identified by iridocorneal malformation, glaucoma, iris stromal hypoplasia, posterior embryotoxon, and corneal opacities.

Read more
Signs & Symptoms

Restrictive Behavior

Restrictive behavior is a form of behavior characterized by an abnormal limitation to a few interests and activities. Children may engage in repetitive motor movements or speech and may continually employ the same routine.

Read more